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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1601 - 15 August Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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History: The patient is an 87 year old woman with shave biopsies of lesions taken from the left temple.

Case Posted by Mark Hurt


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Guest Arash Daryakarr

Posted

I think of sebaceoma.

Hyalinized stroma reminds me of moth eaten appearance.submitted tissue seems to be superficial and i can't evaluate the depth.in some cases,distinction from sebaceous carcinoma is difficult and preferred to recommend total excision of the lesion.

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Dr. Mona Abdel-Halim

Posted

Thought also of sebaceoma with rippled pattern.

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Nitin Khirwadkar

Posted

I would favour a sebaceoma. Agree with Arash's comments above. Has a very nodular pattern of growth, and hence would consider other basaloid tumours with sebaceous differentiation, and do apprpriate IHC.

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Raul Perret

Posted

I agree with sebaceoma and with the comment of Arash

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Mark A. Hurt MD

Posted

My diagnosis was sebaceoma.  I think this group knows this diagnosis well.  When I first encountered it about 25 years or so ago, I was completely baffled.  I thought it was some variation of trichoblastoma (trichoepithelioma).  The "rippled" pattern is a characteristically found, if not specific, phenomenon in these lesions.  In this case, all of the mismatch repair proteins were retained. 

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