Case Number : Case 1463 -02 February Posted By: Guest

Subcutaneous mucin granuloma with epidermal cyst: ?Deep granuloma annulare. Difficult!!!

Angiomyxoma with epidermoid cyst?

Case 1461 (Friday's) now has the original H&E images posted.

Epidermal inclusion cyst and silicone granuloma, or alternatively with encapsulated fat necrosis  

Or other filler (Hyaluronic acid), for penile enhancement in a young male

To be honest I am not sure, I think that small nodule of mucinous material surrounded by histiocytes is indeed due to a foreign material. The topography of the lesion is somewhat disorienting, I would use polarized light to see if there is some birrefringence in those microcystic/vacuolar áreas. 

can the STD like syphilis or other disease in the chronic phase make such pathological changes

Yes, this is a cyst, with steroid injection in the last 3 photos.

Thanks to all you: i'm learning and growing in this web site.