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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1473 -16 February Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Case History: 77 year old male with lesion on right neck.

Case posted by Dr Uma Sundram


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vincenzo polizzi

Posted

Angioleiomyoma.

Angioleiomyoma in the head and neck, a retrospective...

www.ncbi.nlm.nih.gov/pmc/articles/PMC4063654/ 

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Raul Perret

Posted

This is a benign neoplasm without doubt. I think Vincenzo s suggestion of angiolyomioma is a good one but I would still perform IHQ techniques (ck, EMA, desmin, SMA, s-100, CD34) I think on morphology alone we cannot rule out perineurioma and ancient scwhannoma. Some onion bulb sclerotic areas make me think hardly on perineuroma

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Guest Romualdo

Posted

Especially in areas with a pale edematous background I think there is a great resemblance to smooth muscle. I also think this is angioleiomyoma.

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Dr. Mona Abdel-Halim

Posted

I also thought of angioleiomyoma

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Nitin Khirwadkar

Posted

Does look like an angioleiomyoma. Epithelioid perineurioma also crossed my mind. Like Raul has suggested an IHC panel is definitely needed!

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Arti Bakshi

Posted

Angioleiomyoma vs myopericytoma. (Prominent concentric perivascular arrangement)

Both entities probably belong to the same spectrum as overlapping histological features. SMA and H-caldesmom  positive in both, but desmin usually +ve in angioleiomyoma and negative in myopericytoma.

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Uma Sundram

Posted

Angioleiomyoma. Desmin, s100 and EMA were all negative. Great discussion!

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