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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1447- 11 January Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Case History: The patient is a 79-year-old white man with punch biopsies of non-pruritic erythematous papules, some of which are ulcerated, present for two months. The biopsy was taken from the left upper inner forearm.
Case posted by Dr Mark Hurt


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Nitin Khirwadkar

Posted

Pityriasis lichenoides. The biopsy shows a mixed tissue reaction pattern (spongiotic and interface), occasional necrotic keratinocytes, some red cell extravasation and a lymphocytic vasculitis.

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Raul Perret

Posted

It looks like a lichenoid pattern of reaction with parakeratosis, apoptosis at all levels of epidermis with satellite cell necrosis (picture 4)  basal hydropic degeneration, and a dermal lymphocytic perivascular infiltrate without eosinophils. Made me think in first place of Graft vs Host disease but clinical correlation is critical and differential wide.

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Arti Bakshi

Posted

Agree with Nitin...PLC/PLEVA spectrum. The clinical would suggest more 'acuta' than 'chronica'.

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Dr. Mona Abdel-Halim

Posted

Yes Pityriasis Lichenoides, mostly acuta due to the presence of ulcerated lesions.

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Guest Romualdo

Posted

Agree with pityriasis lichenoides, most probably PLEVA.

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vincenzo polizzi

Posted

I see an alternating orto parakeratosis PRP-like, but clinical and many histological findings convince me ti PLEVA

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