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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1553 - 08 June Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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76 year-old male with biopsy from abdomen.

Dr Hafeez Diwan



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Raul Perret

Posted

Acute subepidermal cell poor bullous disease with confluent epidermal necrosis. Clinicopathologic correlation is essential.  Should consider SJS/TEN mainly but there are some differentials and depends of diffuse/localized distribution etc.. 

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Guest Charlie Keen

Posted

I need a little more haematoxylin and some higher powers. I agree there is a suggestion of something viral...

I also need some more clinical description of the lesion(s)...

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Nitin Khirwadkar

Posted

Some of the sections look like a DPAS. Not sure what is going on... focally infarcted, Cant see definite viral inclusions or fungi. Some bacterial debris . Other necrotising lesions? Need more history.

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Dr. Hafeez Diwan

Posted

Toxic epidermal necrolysis.  This was the clinical impression as well. 

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