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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1505 - 31 March Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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65/F Persistent facial erythematous rash?lupus, ?seborrhoiec dermatitis

Dr Arti Bakshi


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vincenzo polizzi

Posted

What about pemphigus foliaceus, erythematous variant(Senear-Usher syndrome)?

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Raul Perret

Posted

pemphigus erythematosus (Senear-Usher syndrome) 

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Pemphigus erythematosus. Had two cases like this in this month with similar hypothesis. Nice.

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Agree with pemphigus erythematosus.  IMF for confirmation. 

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Dr. Mona Abdel-Halim

Posted

We have lots and lots of pemphigus (of all types) in our hospital..

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superficial pemphigus mostly pemphigus erythematosus   For IMF  

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This site is a good  teaching site. Many thanks for DR mona Abdalahalim as she informed me by this site in 2013. it was the main reason for my passing  international board exam in dermatopathology december 2015.

many thanks for this teaching site and special thanks for dr mona abdalhalim

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Guest Arash Daryakarr

Posted

Agree with colleagues.Pemphigus erythematosus.IF may show a lupus band like deposition in addition to intercellular epidermal fluorescence.

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Dr. Mona Abdel-Halim

Posted

You are most welcome Dr Sadat, a new Egyptian certified dermatopathologist :-)

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Arti Bakshi

Posted

Yes, this is superficial pemphigus.

The IMF showed intercellular positivity for IgG, but no dermo-epidermal positivity for immunoglobulins or C3. Also ANA was negative, so I called this pemphigus foliaceous rather than pemphigus erythematosus. 

 

 

Congrats to Sadat!! This is indeed an extremely educational website.

Would urge members who regularly visit spot diagnosis, but do not put in a diagnosis to do so. Its the best way to learn. Do not be afraid of making mistakes, we are all learning here!

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