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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1693 - 23 November - Dr Hafeez Diwan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 47 year-old female with biopsy of nasal lesion. Contributing pathologist wanted to rule out SCCIS.

Case Posted by Dr Hafeez Diwan


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Admin_Dermpath

Posted

A compact case for you all to work on today by Dr Hafeez Diwan

 

Geoff Cross - DermpathPRO Projects

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I did not see any sign of malignancy. I can see some keratinoyte binucleation with nuclei showing pale and graund-glass inclusions. I think this is HSV infection. 

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Raul Perret

Posted (edited)

The last image shows clear nuclear inclusions and multinucleation. Herpes as vincenzo suggested

Edited by Raul Perret

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Robledo F. Rocha

Posted

I don’t think this is carcinoma in situ. On the other hand, signs of herpes virus infection are present, to wit, epidermal necrosis with ulceration, keratinocytes nuclei with ground-glass appearance, binucleation, cytoplasmic vacuolization, and acantholysis.

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