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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1636 - 3 October Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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F25. Lump thigh. c/o Dr Alex Kitchen. H&Ex8

Case Posted by Dr Richard Carr


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Nitin Khirwadkar

Posted

Clear cell hidradenoma. Would do a small IHC panel to rule out usual mimics and demonstrate ducts.

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vincenzo polizzi

Posted

Age and very low nuclear grade ( TFE3pos of young people RCC r usually higher grade) and hyaline material and absence of red cells make me favor CCH. But IHC and CPC is mandatory.

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Agree. Clear cell hidradenoma. IHQ to exclude clear cell RCC.

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Alice Roberts

Posted

I also agree with clear cell hidradenoma

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Dr. Richard Carr

Posted

Yes this was a nice example of a typical clear cell hidradenoma.  Referred with supportive immunohistochemistry (EMA ++20% highlighting cystic areas; CEA polyclonal lines cystic spaces, Cam5.2 highlights lining and peri-lining cells. RCC marker -ve; S100-ve. PAS not much glycogen or mucin).

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