Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1797 - 18 April - Dr Uma Sundram Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

Clinical History: 64 year old male with 9 mm right inferior lip lesion.

Case Posted by Dr Uma Sundram


  Report Record

User Feedback


vincenzo polizzi

Posted

It seems like a hybrid myxoid nerve sheath tumor and cellular neurothekeoma...

Share this comment


Link to comment
share_externally

Raul Perret

Posted (edited)

Due to the clinical description I would consider in my differential an irritation fibroma (a bit more cellular than routine cases). However, a small ihc panel should be performed (cd34, s-100) to confirm the diagnosis.

Edited by Raul Perret

Share this comment


Link to comment
share_externally

vincenzo polizzi

Posted

Yes Raul, I think you hit the nail on head. Due to the abundant myxoid background and the cellularity I didn't think of it.

Share this comment


Link to comment
share_externally

Dr. Mona Abdel-Halim

Posted

Agree with irritation fibroma

Share this comment


Link to comment
share_externally

Sasi Attili

Posted

Never heard of an irritation fibroma. But the histo is in the the cellular fibroma family...

Share this comment


Link to comment
share_externally

Dr. Richard Carr

Posted

Nice to hear of new or old things! Despite the lack of an adipocyte I could not get spindle cell lipoma out of my head on this case.

Share this comment


Link to comment
share_externally

Uma Sundram

Posted

Great discussion! The lesion is factor XIIIA strongly positive, and is somewhat cellular for an oral fibroma. We suggested the possibility of an intraoral dermatofibroma to the clinician and he thought that was a good clinical fit. S100 and CD34 are both negative. Cellular neurothekeoma is another good thought. NKIC3 can be positive in both DF and cellular neurothekeoma; somewhat unusual location for both lesions.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...