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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1963 - 7 Dec 2017 Posted By: Nitin Khirwadkar

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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44 M, Few areas on the skin of the back of neck with a ‘plucked chicken appearance’


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Dr. Richard Carr

Posted

Nitin, great to see you posting on the site. Warm regards R.

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vincenzo polizzi

Posted

Pseudoxanthoma Elasticum (odd age, but PXE is often asymptomatic, so it may present in adult age ). 

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vincenzo polizzi

Posted

2 hours ago, Raul Perret said:

 

Agree with the nice clinical description.

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Nitin Khirwadkar

Posted

Yes, pseudoxanthoma elasticum (PXE). Very typical histology. The Von Kossa and EVG stains highlighted the abnormal elastic fibres. I shall request admin to upload these. A leading clinical clue on the request form! The patient had a cardiological examination which was normal.  The patient had bilateral angioid streaks. It is important to remember that PXE has a striking variation in the phenotypic expression and not all patients will manifest with cutaneous lesions.

P.S. Thanks Richard and all.

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