Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1754 - 16 February - Dr Arti Bakshi Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

Clinical History: 20/F, 3cm pedunculated hyperkeratotic lesion back of thigh since childhood.

Case Posted by Dr Arti Bakshi


  Report Record

User Feedback


Admin_Dermpath

Posted

To mark my favourite middle daughter, Jenny's 25th Birthday, Dr Arti Bakshi has a great case for you all.

 

Geoff Cross - DermpathPRO Projects

Share this comment


Link to comment
share_externally

Arti Bakshi

Posted

many happy returns to Jenny!  If I'd known, i would have put in something much nicer than these warty bits of skin!! 

Share this comment


Link to comment
share_externally

Raul Perret

Posted

I thought this is a warty lesion with papillomatosis, acanthosis, epidermolytic hyperkeratosis and foci of SCAP. So as there is a combination of lesions I thought of naevus sebaceous. 

Share this comment


Link to comment
share_externally

The location is atypical, but my diagnosis is also Nevus sebaceous with Syringocystadenoma papilliferum.

Share this comment


Link to comment
share_externally

vincenzo polizzi

Posted

This is an exophytic epidermal proliferation with papillated  structures and columns of hyperkeratotic mass associated with    cystic invaginations typical of syringocystoadenoma papilliferum.How about an "apocrine acrosyringeal keratosis associated with syringocystoadenoma papilliferum?

https://www.ncbi.nlm.nih.gov/pubmed/?term=Yamamoto M[Author]&cauthor=true&cauthor_uid=10735969

Share this comment


Link to comment
share_externally

Dr. Mona Abdel-Halim

Posted

Happy BD to Jenny :-))

SCP 

back ground apocrine acrosyringeal keratosis is a lovely suggestion by Vincenzo :-)

Share this comment


Link to comment
share_externally

Robledo F. Rocha

Posted

Site is unusual, but I agree with my colleagues. This is a nevus sebaceus of Jadassohn with verrucous acanthosis of the epidermis and postpubertal development of syringocystadenoma papilliferum.

Share this comment


Link to comment
share_externally

Arti Bakshi

Posted

Yes, I went for SCAP too with verrucous acanthosis and raised possibility of Naevus Sebaceous. Agree, site is ODD!!

Kazakov mentions this as a specific variant of SCAP (pg 65) ie. Viral wart like changes in SCAP or Verrucous SCAP and many of these are associated with naevus sebaceous. Apparently the surface epidermal changes not just mimic a vral wart but HPV DNA has been detected by PCR and ISH in some lesions leading to reports of condyloma acuminatum in association with SCAP. https://www.ncbi.nlm.nih.gov/pubmed/7864300.

Vincenzo's suggestion is also interesting and probably represents the same spectrum.

 

 

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...