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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1757 - 21 February - Dr Uma Sundram Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 35 year old woman with lesion on back, thought clinically to be a lipoma.

Case Posted by Dr Uma Sundram


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Admin_Dermpath

Posted

Dr Uma Sundram provides today's Spot Diagnosis Case to test you all, enjoy

 

Geoff Cross - DermpathPRO Projects

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vincenzo polizzi

Posted

Even though there is something of clear cell variant of BCC ( peritumoral stromal retraction  and peripheral epithelial palisades ) I think of an adnexal benign tumor of ductal sweet glands: a Clear Cell variant of Nodular Hidradenoma. There's a MF in last fig, but hidradenoma may contain some mitosis.

Nice similarity to canalicular basal cell adenoma of salivary glands. 

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Robledo F. Rocha

Posted

A solid tumor composed of epithelial cells with clear eosinophilic cytoplasm which are arranged in an, at least focally, intriguing trabecular/labyrinthine pattern usually seen in sebaceous tumors. Although I didn’t find unequivocal evidence of glandular/ductal differentiation nor the typical hyalinized stroma, I agree this is hidradenoma.

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Raul Perret

Posted

I though of hidradenoma with clear cell change but would also do immunos to rule out trichoblastoma with prominent clear cell change

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Alice Roberts

Posted

I'm thinking clear cell hidradenoma or trichoblastoma

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Sasi Attili

Posted

17 hours ago, Raul Perret said:

I though of hidradenoma with clear cell change but would also do immunos to rule out trichoblastoma with prominent clear cell change

agree

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Uma Sundram

Posted

Hidradenoma with clear cell change.  I sent this case in consultation to Dr. Mark Wick who agreed with the diagnosis. Adipophilin was negative.

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