Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1724 - 5 January - Dr Arti Bakshi Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

Clinical History: 40/M, lesion forehead.

Case Posted by Dr Arti Bakshi


  Report Record

User Feedback


Admin_Dermpath

Posted

Beautiful images from Dr Arti Bakshi.

 

Happy New Year, Geoff Cross - DermpathPRO Projects

Share this comment


Link to comment
share_externally

Dr. Mona Abdel-Halim

Posted

What about panfolliculoma? I can see in the fifth image esinophilic THG indicative of matrical differentiation in addition to areas with hair germ differentiation (with papillary mesenchymal bodies), in addition to infundibular and trichilemmal keratinization?

Share this comment


Link to comment
share_externally

Robledo F. Rocha

Posted

2 hours ago, Dr. Mona Abdel Halim said:

What about panfolliculoma? I can see in the fifth image esinophilic THG indicative of matrical differentiation in addition to areas with hair germ differentiation (with papillary mesenchymal bodies), in addition to infundibular and trichilemmal keratinization?

I fully agree with you, Mona!

Share this comment


Link to comment
share_externally

vincenzo polizzi

Posted

When I see a trichofolliculoma-like  tumor, with trichoblastic and matrical epithelial components and an evident mesenchimal-body type stroma, I think of PANFOLLICULOMA, so I agree with Mona and the above. 

Share this comment


Link to comment
share_externally

Arti Bakshi

Posted

Apologies for the late reply...I have been on holiday with limited internet connection!

Yes, my d/d was TF and cystic panfolliculoma too. The panfollicular differentiation is quite well seen with follicular germinative cells with specific follicular stroma, inner root sheath differentaition with bright red trichohyalin granules and infundibular differentiation.

Both trichofolliculoma and panfolliculoma show panfollicular differentiation. Trichofolliculomas show a typical silhouette of central cyst like infundibulum with  vellus follicles radiating from it. Although panfolliculoma tend to be more solid and multinodular, cystic panfolliculomas show an architecture rather similar to TF. According to Kazakov, ''so called cystic panfolliculoma may in fact be a variant of Trichofolliculoma''. I think the distinction depends on greater dominance of immature germinative elements in PF as opposed to more advanced follicular diffrentiation in TF. Based on this, a cystic panfolliculoma was favoured in this case.

Thanks for all your comments.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...