Case Number : Case 1855 - 07 July - Dr Iskander Chaudhry (Invited) Posted By: Guest

Botryomycosis / actinomycosis - grain with a granulomatous reaction

Thought of aneurysmal fibrous histiocytoma. 

Lots of views but not many responses :( 

Special stains were negative. 

Hope to get more responses  ......

Iskander

Looks like a foreign body reaction to extraneous matter...not sure about the nature of this extraneous brown material though!

Maybe this is a trauma-induced lesion. The golden-colored material resembles some pigment produced by the breakdown of hemoglobin, like hematoidin.

Looks like a localized form of hemosiderosis which can be caused by many entities, for example acne.

An old organized trombus?

Looks like hemosiderin within a thrombus. Certainly in the last image, the pigment is within a vessel.

Many thanks everyone!

I have added the Perl's stain! 

Yes the diagnosis was localized form of hemosiderosis - as stated the causes are many. 

Iskander Chaudhry