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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1868 - 26 July - Dr Diwan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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66 year-old female with left upper eyelid lesion. Clinical impression: hordeolum internum.

Edited by Admin_Dermpath


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vincenzo polizzi

Posted

Keratin-derived Amyloidosis in BCC

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Dr. Mona Abdel-Halim

Posted

Worried about those cells with bubbly cytoplasm in the epidermis. Seb carc? 

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Victor Delgado

Posted

BCC with some amyloid like material, agree Vincenzo.

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Raul Perret

Posted

I had the same feeling as Mona, I am worried about the cells in the epidermis, maybe some pagetoid spread of sebaceous carcinoma. Would definitely perform immunos in this case.

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Robledo F. Rocha

Posted

I can discern intraepidermal scatter of cells with ample multivacuolated cytoplasm. Agree with Mona and Raul, this is pagetoid spread of periocular sebaceous carcinoma.

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Nitin Khirwadkar

Posted

Agree with Mona, Raul and Robledo, pagetoid spread of sebaceous carcinoma/ in-situ sebaceous Ca.

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Dr. Hafeez Diwan

Posted

Sebaceous carcinoma in situ.  Adipophilin was focally positive.

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