Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1835 - 9 June - Dr Richard A Carr Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

Clinical History: M80. Vascular papule on the right forearm.

Case Posted by Dr Richard A Carr


  Report Record

User Feedback


Admin_Dermpath

Posted

Another great set of images from Dr Richard A Carr.

Geoff Cross - DermpathPRO Projects

Share this comment


Link to comment
share_externally

vincenzo polizzi

Posted

Bowenoid transformation in Seborrheic Keratosis  

It’s a rare event but the bottom line is: histopathological examination of all SKs should be considered!!!

https://www.researchgate.net/profile/Mehdi_Eftekhari/publication/233984832_Bowenoid_transformation_in_seborrheic_keratosis_A_retrospective_analysis_of_429_patients/links/00463528c711c00f91000000.pdf?disableCoverPage=true

Share this comment


Link to comment
share_externally

Raul Perret

Posted

For me there is a component of small cells with high N/C ratio that look poroid. There is also some necrosis en masse and ductular areas, what about CEA expression in this lesion? on the other hand the squamous component looks atypical and has some features of follicular SCC (trichilemmal keratinization and mucin). Architecture looks like well circumscribed/ in situ, I would go with SCC with poroid/ductal differentiation

Share this comment


Link to comment
share_externally

Dr. Mona Abdel-Halim

Posted

I thought of follicular SCC

Share this comment


Link to comment
share_externally

Josie Bisi

Posted

I thought porocarcinoma. I would do IHQ

Share this comment


Link to comment
share_externally

Dr. Richard Carr

Posted

I reported this as a rather basaloid (BerEP4-/EMA+), focally pigmented, follicular SCC. The typical features being the rather rounded profile at the peripheries (clinically mimics BCC), abrupt connections with the epidermis and in foci direct connections with follicular infundibula. Absence of adjacent bowen's/AK. Prominent intra-epithelial, stromal type (follicular) mucin and distinctive centrally located pilar type keratinisation. This is really a very typical example of the rather indolent looking, circumscript type, probably mainly an in situ lesion (pushing only borders) and probably does not need follow-up as for "conventional" invasive SCC. A small number of follicular SCC (<10%) in our experience have areas of focally prominent pigmentation with reactive appearing dendritic melanocytes). We have seen one dramatic case that mimicked SSMM clinically and have collected a modest series (as yet unpublished). Perhaps the melanocytes are somehow stimulated in follicular as opposed to "conventional" SCC (actinic keratosis related) in which I have rarely seen pigmentation. Pigmented bowen's is well described particularly in genital locations.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...