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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1763 - 1 March - Dr Hafeez Diwan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 36 year-old female with 10.5 cm mass on left trunk.

Case Posted by Dr Hafeez Diwan


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Admin_Dermpath

Posted

I am away recording an FRCPath Mock Exam Course today and tomorrow so here is tomorrow's case a day early, enjoy.

 

Geoff Cross - DermpathPRO Projects

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This tumor composed of  uniform small spindle cell with plump nuclei, storiform pattern, honeycomb appearance...So this is a DFSP.

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Raul Perret

Posted (edited)

Agree with dfsp, cells in pic 2 and 3 have a more primitive look and the pattern looks more fascicular and herringbone. I think it would be important to check cd34 in those areas as I think this is fibrosarcomatous transformation. The tumor is 10 cm too so that is another alarming feature

Edited by Raul Perret

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vincenzo polizzi

Posted

Agree with DFSP. 

I see a herringbone pattern in fig2, too; but there isn't any cellular crowding, increasing atypia or pleomorphism, or other changes of tumoral dedifferentiation. So my spot diagnosis is of classic dermatofibrosarcoma protuberans.

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Nitin Khirwadkar

Posted

DFSP. Agree with Raul's comments regarding sarcomatous transformation.

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Robledo F. Rocha

Posted

Dermatofibrosarcoma protuberans.

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Dr. Hafeez Diwan

Posted

CD34 was diffusely positive.  DFSP with fibrosarcomatous transformation.

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