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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1766 - 6 March - Dr Limin Yu Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 5 month-old boy, head mass. cd68 +, s100 -, cd1A -, Mart-1 -.

Case Posted by Dr Limin Yu


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Admin_Dermpath

Posted

Get your week off to a bumper start with a bumper set of images for Dr Limin Yu's Spot Case.

 

Geoff Cross - DermpathPRO Projects

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Victor Delgado

Posted

Spindle Cell Xanthogranuloma

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vincenzo polizzi

Posted

JXG my first thought ( Touton cells poor ). 

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Mariantonieta Tirado

Posted

I agree with spindle cell xanthogranuloma but I would add langerin (CD207) to the panel

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JXG,  even without typical Touton

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Robledo F. Rocha

Posted

Juvenile xanthogranuloma.

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Sasi Attili

Posted

Looks like JXG- but quite a large mass!

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Limin Yu

Posted

I agree with everyone -- I called it JXG, too

There are abundant eosinophils. I don't recall I have seen a JXG with so many eosinophils.  That's why I performed immunostains to rule out other possibilities. 

 

Kinda curious anyone has seen so many eos in JXG. Thanks!

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