Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1784 - 30 March - Dr Arti Bakshi Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

Clinical History: 48 female, lesion, 3rd toe, right foot, shave biopsy.

Case Posted by Dr Arti Bakshi


  • Like 1
  Report Record

User Feedback


vincenzo polizzi

Posted

An acral dome shaped lesion containing fascicles and loose storiform structures of spindle and stellate cells, in abundant myxo-vascular stroma. My first impression is : Superficial Acral Fobromyxoma.  

Share this comment


Link to comment
share_externally

Raul Perret

Posted

cellular digital fibroma (which probably and as we discussed previously is a variant of superficial acral fibromyxoma). here and here

Share this comment


Link to comment
share_externally

Raul Perret

Posted

Forgot to add that this is a shave biopsy so should be cautious on the final diagnosis as we cannot see the tumor front.

Share this comment


Link to comment
share_externally

I would like to add as a differential diagnosis the Sclerotic perineurioma. EMA could be of great help.

Share this comment


Link to comment
share_externally

Dr. Mona Abdel-Halim

Posted

My first impression was perineurioma , sclerotic .

Share this comment


Link to comment
share_externally

vincenzo polizzi

Posted

Probably CDF and SAFM are the same lesion...however the first is usually reported as a more superficial tumor on dermis, and here, according with Raul, we can't see the tumor front. I favour SAFM because there is a typical alternating pattern of myxoid and collagen stroma, there is a well developed vascular network, and, above all, doesn't look like a DFSP, as CDF does!!!

Perineurioma is another good differential! I confess I hadn't think before.

Share this comment


Link to comment
share_externally

Sasi Attili

Posted

Agree CDF or SAFM - both probably have a degree of overlap. 

Share this comment


Link to comment
share_externally

Alice Roberts

Posted

Superficial acral fibromyxoma. CD34 IHC stain helpful.

Share this comment


Link to comment
share_externally

Robledo F. Rocha

Posted

Agree with the spectrum of superficial acral fibromyxoma / cellular digital fibroma, bearing in mind Raul's caveat this is a partial biopsy.

Sclerosing perineurioma is an excellent differential diagnosis, but its marked predilection for the hands makes it less likely.

Share this comment


Link to comment
share_externally

Arti Bakshi

Posted

I went for Superficial acral fibromyxoma too.

The lesion  was CD34, CD99 and CD10 positive. Perineurioma was my top differential too, but EMA was negative.

Agree with all the comments made regarding overlap with CDF!

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...