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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1818 - 17 May - Dr Hafeez Diwan Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 59 year-old female with history of right parotid mucinous adenocarcinoma metastatic to lung who presented with 8-month history of right infraorbital lesion. P63 immunostains are shown in two different parts of this tumor.

Case Posted by Dr Hafeez Diwan


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Admin_Dermpath

Posted

Dr Hafeez Diwan has given you lots of images to help you with your Spot Diagnosis.

Geoff Cross - DermpathPRO Projects

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vincenzo polizzi

Posted

Primary cutaneous invasive mucinous ( eccrine/apocrine ) carcinoma, with nice myoepithelial-marked in situ component.

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Robledo F. Rocha

Posted

Mucinous carcinoma. The intact peripheral myoepithelial cell layer, highlighted by immunohistochemistry, demonstrates the in situ component. Ipso facto, this tumor is not a metastatisis from the parotid neoplasm, but has arisen primarily in the skin.

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Dr. Hafeez Diwan

Posted

In my opinion, this has features of both endocrine mucin-producing sweat gland carcinoma and mucinous carcinoma.  There are in situ and invasive components and one could speculate that the mucin-producing carcinoma may be the in situ component of the invasive mucinous carcinoma.  That there may be an association between these lesions has been suggested by some authors.  

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