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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1821 - 22 May - Dr Limin Yu Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical History: 34 year-old Female, right thigh mass.

Case Posted by Dr Limin Yu


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Admin_Dermpath

Posted

A round dozen images for you to work on today from a great case by Dr Limin Yu.

Geoff Cross - DermpathPRO Projects

 

Only two weeks to go: 

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9th & 10th June 2017

 

Running in its second year, with excellent feedback from delegates!

A two day practical course in Dermatopathology designed for dermatologists, pathologists, residents, fellows and faculty. 

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vincenzo polizzi

Posted

What about a "Cutaneous (superficial) Angiomyxoma"?

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vincenzo polizzi

Posted

"What about a "Cutaneous (superficial) Angiomyxoma"?"

thought a lot of a dermal nerve sheath myxoma, but favour SAM. 

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Raul Perret

Posted

Agree with the differential diagnosis IHC would be helpful. The pictures do not show a prominent vascular network or neutrophils that are frequently seen in SAM but there are some trapped follicles and giant cell reaction that although not specific are usually in this entity. Here a nice article of Fletcher and Calonje that we recently shared with Sasi Attili and highlights the importance of ruling out Carney syndrome when multiple lesions are present.

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Raul Perret

Posted

Forgot to mention that another diff dx to consider in this kind of case is myxoid neurofibroma, although morphologically I do not favour this dx

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Dr. Mona Abdel-Halim

Posted

First impression: nerve sheath myxoma. 

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Robledo F. Rocha

Posted

Agree with superficial angiomyxoma. Clinical presentation of a solitary lesion located away from eyelid, ear, and nipple favors a sporadic tumor rather than association with the Carney complex.

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Dr. Mona Abdel-Halim

Posted

Agree with sup angiomyxoma after looking again at the last 4 photos :-)

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Nitin Khirwadkar

Posted

Superficial angiomyxoma.

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Limin Yu

Posted

Diagnosis: nerve sheath myxoma S100+, cd68+, cd34+

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Sasi Attili

Posted

3 hours ago, Limin Yu said:

Diagnosis: nerve sheath myxoma S100+, cd68+, cd34+

Interesting case. Question- how do we differentiate from myxoid NF?

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Dr. Mona Abdel-Halim

Posted

So always stick to first impression !!!!

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