Case Number : Case 1827 - 30 May - Dr Uma Sundram Posted By: Guest

We are a little late with this case as we all catch up from last week's London Dermatopathology Symposium. But well worth the wait, a lovely case by Dr Uma Sundram.

Geoff Cross - DermpathPRO Projects

Nevoid melanoma. Melanina and mitosis at the botton 

An epithelioid and spindle cell component, with random atypia and dermal mitosis, is present in deep dermis, surrounded by a banal dermal nevus.  The atypical component doesn't grow as an expansive nodule, but is intermixed and integrated with the  nevus. So I'm thinking of a combined nevus, dermal and DPN.  

For me this is a clonal nevus

I am thinking of clonal nevus as Raul said

An otherwise regular and symmetric proliferation of two distinct populations of melanocytes with low mitotic activity and some (senescent) nuclear atypia. I go with melanocytic nevus with phenotypic heterogeneity combining common nevus and cellular blue nevus (or deep penetrating nevus).

yes, agree with a combined naevus. Appears to be a combination of DPN and common naevus.

Yes, apologies for the late post and kudos to geoff for being a star and saving me from embarrassment! Thank you for your wonderful comments and you are spot on. Combined nevus, ordinary type and cellular blue. DPN would have worked just as well.