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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1936 - 31 Oct - Dr Iskander Chaudhry (invited) Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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40 year old male, Left ear excision Dysplastic naevus. ?MM

Edited by Admin_Dermpath


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vincenzo polizzi

Posted (edited)

Combined nevus, deep penetrating(with a clonal type B component), and common intradermal nevus. I don't think this is a nevoid melanoma.

Edited by vincenzo polizzi

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I favor intradermal nevus.

One dermal melanocytic mitotic figure would buy this case deeper cuts to look for more mitoses, and more than one mitosis would necessitate some stains. Ki67 or Ki67/Melan-A for proliferative rate, HMB-45 for maturation gradient, and I generally throw in P16 to see if it is nicely retained as an additional measure of reassurance.

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Admin_Dermpath

Posted

Dear All Dr Chaudhry has added 2 markers to assist you. Best wishes Admin. 

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Iskander H. Chaudhry

Posted

Yes final diagnosis was a benign intradermal naevus. Just looks worrying at the first glance! 

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