Case Number : Case Number : Case 1916 - 03 Oct - Dr Uma Sundram Posted By: Guest

generalized granuloma annulare?

Compact hyperkeratosis, slight acanthosis, subtle mucin deposition in upper and mid dermis, thickened collagen bundles and perivascular lympho- histiocytic infiltrate with a few eosinophils. Suggestive of papular mucinosis

Mmmh! Without any clinical history, I would have thought of a perniosis or chilblain lupus...It seems an acral biopsy. But it is a generalized  rash.  Erythema annulare centrifugum? But without parakeratosis and with so much papillary dermal edema?

I haven’t any spot diagnosis for the moment. Waiting for some suggestions of my Colleagues...

Also thinking of lupus tumidus...

GA, mostly interstitial type. 

Generalized GA

Reactive granulomatous dermatitis which include interstitial granulomatous dermatitis, PNGD, and Interstital granulomatous drug reaction.

This disorder might be associated with rheumatoid arthritis.

You may appreciate the floating sign; histiocytic infiltrate surrounding clefted floating foci of piecemeal degenerated collagen.

Interstitial granulomatous dermatitis. A drug etiology was suspected.

Sorry, I wish to clarify - a drug etiology was suspected clinically.