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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1905 - 15 Sept - Dr Richard Carr Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Clinical Details: F50. Swelling on left middle finger. ?Ganglion but not connected to joint.


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Raul Perret

Posted

Beautiful Nerve sheath myxoma with classic lobular architecture and multiple ring-like structures

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vincenzo polizzi

Posted

There are two acral neoplasms with pseudolipoblasts cells: Acral Myxoinflammatory Fibroblastic Sarcoma(alias Inflammatory Myxohyaline Tumor of Distal Extremities) and Nerve Sheath Myxoma(the lipoblasts-like cells are occasionally abundant).

The first has got a conspicuous inflammatory component and many hyalinized or ganglion-like cells often Sternberg-like, totally absent in this case. So totally agree with Raul!

Very great case.

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Dr. Mona Abdel-Halim

Posted

Nice case! Agree with nerve sheath myxoma.

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Dr. Richard Carr

Posted

Yes this is a (dermal) nerve sheath myxoma. Nicely diffusely S100 positive (not shown). Anatomic location is typical. I think they must be quite rare as I had not seen a "hot" case for many years almost to the point of forgetting what they look like. I was very struck by the ring-like structures in this case which are illustrated in some texts. 

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