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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2145 - 29 August 2018 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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35 year old female lesion on arm ? MM
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Edited by Admin_Dermpath

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Krishnakumar subramanian

Krishnakumar subramanian 0

Posted

nodular amelanotic melanoma

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dermpath1

Type A Nevus.

Testing for BAP1 loss will be of interest.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

BAPOMA is my first impression

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Admin_Dermpath

Admin_Dermpath 1,212

Posted

Dr Chaudhry response:

BAPoma: it lacks the 2 cell population, is not really polypoid and the cells are not quite right.

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vincenzo

Asymmetric and nodule-expansive. I think this is a small cell nodular melanoma.

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vincenzo

vincenzo 4

Posted (edited)

Please Dr Chaudry, what's the diagnosis of case 2125?

Edited by vincenzo

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Admin_Dermpath

Admin_Dermpath 1,212

Posted

Dr Chaudhry's response:

The lesion showed: no loss of BAP1 expression by IHC. HMB45 stained the upper part of the lesion and Ki67 was 20% in the same area (upper part). This was a difficult case to characterise but after several opinions it was felt the junction was definitely in situ melanoma and on balance the entire lesion was a malignant melanoma and should be treated as such. 

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