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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2095 - 18 June 2018 Posted By: Limin Yu

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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51 year old male, lesion to forehead.


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dermpath1

Posted

Clear cell BCC is a consideration.

But I have same opinion of Anil, that this may represent a rare variant of Bowen; Warty and clear cell Bowen's disease (WCCBD) or rather clear cell type of Bowen .This type usually occur on the temple, and  has been linked to HPV.

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dermpath1

Posted

Just to add intraepidermal sebaceous (or sweat glands)  neoplasms are down in the list of DDX.

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vincenzo polizzi

Posted

It could be an intraepidermal component of sebaceous carcinoma. 

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vincenzo polizzi

Posted

If the pictures represent the entire lesion, this is a sebaceous in situ carcinoma. 

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Limin Yu

Posted

Thank everyone for the insightful discussion. This is an SCCIS with pagetoid spread. DDX includes MIS, sebaceous carcinoma in situ and EMPD. 

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