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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2030 - 16 March Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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F30. Vulvar plaques with exophytic nodule. History of systematised non-epidermolytic epidermal naevus since childhood.


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vincenzo polizzi

Posted

Verruciform Xanthoma, with some koilocytic features. Interestingly HPV infection has been reported in several cases of VX as causative agent. 

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Anil Patki

Posted

Cauliflower-like growth, koilocytic changes and dermal inflammatory changes make me think of condyloma acuminata

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2 hours ago, Anil Patki said:

Cauliflower-like growth, koilocytic changes and dermal inflammatory changes make me think of condyloma acuminata

 

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LR123

Posted (edited)

Verruciform Xanthoma.

There is necrosis of the keratinocytes with neutrophils and foam cells  in the dermal papillae! I didn’t appreciate koilocytic changes !

Edited by LR123

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John Zhang

Posted

Some foamy cells in the papillary dermis, Verruciform xanthoma.

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Dr. Richard Carr

Posted

Case c/o Dr Benedicte Cavelier-Balloy.

Diagnosis: Verruciform xanthoma (VX) associated with systematised epidermal naevus.

On my last reading there was not a specific association between VX and HPV as far as I am aware.

Other cases of VX on Spot diagnosis: 1028 (MH), 1435 (HD), 1771 (RC), 1781 (LY), 1879 (RC).

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