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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2030 - 16 March Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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F30. Vulvar plaques with exophytic nodule. History of systematised non-epidermolytic epidermal naevus since childhood.
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Go to records March 2018

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vincenzo polizzi

vincenzo polizzi 185

Posted

Verruciform Xanthoma, with some koilocytic features. Interestingly HPV infection has been reported in several cases of VX as causative agent. 

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Anil Patki

Anil Patki 4

Posted

Cauliflower-like growth, koilocytic changes and dermal inflammatory changes make me think of condyloma acuminata

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LR123
2 hours ago, Anil Patki said:

Cauliflower-like growth, koilocytic changes and dermal inflammatory changes make me think of condyloma acuminata

 

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LR123

LR123 0

Posted (edited)

Verruciform Xanthoma.

There is necrosis of the keratinocytes with neutrophils and foam cells  in the dermal papillae! I didn’t appreciate koilocytic changes !

Edited by LR123

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John Zhang

John Zhang 0

Posted

Some foamy cells in the papillary dermis, Verruciform xanthoma.

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Dr. Richard Carr

Dr. Richard Carr 622

Posted

Case c/o Dr Benedicte Cavelier-Balloy.

Diagnosis: Verruciform xanthoma (VX) associated with systematised epidermal naevus.

On my last reading there was not a specific association between VX and HPV as far as I am aware.

Other cases of VX on Spot diagnosis: 1028 (MH), 1435 (HD), 1771 (RC), 1781 (LY), 1879 (RC).

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