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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2073 - 17 May 2018 Posted By: Raul Perret

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Case 56: 45 y old female with a 20-30 mm superficial lesion located in the breast.
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Go to records May 2018

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vincenzo polizzi

vincenzo polizzi 185

Posted

Yes! Breast Nodular Fasciitis. 

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Raul Perret

Raul Perret 262

Posted

Yes well done, this is a case of nodular fasciitis of the breast. The myofibroblastic cells were positive for smooth muscle actin and negative for h-caldesmon. We also frequently perform HMGA2 that is a sensitive but unspecific maker for nodular fasciitis (in this case it was positive). Due to the presence of necrosis (figure 3), which is an infrequent finding, the referring pathologist asked for confirmation of the diagnosis by USP6 break appart FISH that was indeed positive.

Have a nice weekend

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Arash Daryakar

Arash Daryakar 11

Posted

very nice and well documented case dear Raul.

Thanks!

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