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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2171 - 4 October 2018 Posted By: Raul Perret

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Acral lesion of a 30 year old male.

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John Zhang


glomus tumor with mucinous changes. Need keratin (negative) and SMA (positive) to confirm.

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Raul Perret


Yes, this is a glomus tumor. Due to the myxoid stroma and the aspect of the cells, myoepithelioma is in the differential. Pic 3 shows some ramified vessels that are not characteristic of myoepithelioma but can be seen in pericytic tumors. H-caldesmon permits to confirm the diagnosis. Have a good weekend

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