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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2296 - 2 April 2019 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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48 year old woman with new lesion on left flank. No lesions elsewhere, otherwise healthy


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The top of my differential diagnosis is a metastasis, particularly from the breast. Once I can completely rule out that possibility, I will start thinking.

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Krishnakumar subramanian

Posted

agreed first r/o metastatic deposits from breast ca

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First spot: metastatic lobular breast carcinoma. 

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Alex-Ventura-Leon

Posted

Difficult to think in another differential than Metastatic Carcinoma (also agree that my first possibility would be a lobular breast carcinoma)

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Dr. Mona Abdel-Halim

Posted

Yes metastasis mostly breast

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Uma Sundram

Posted

Yes, we were quite concerned about metastatic breast carcinoma and could not rule it out based on the histology. It's a fairly recent case and I have no further information. I have not seen any skin adnexal tumors look quite this way. The tumor is CK7 positive and CK20 negative.

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If you do GATA-3 and ER/PR, that should nail the diagnosis of metastatic breast carcinoma.

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Krishnakumar subramanian

Posted

madam what is the final diagnosis

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