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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2304 - 12 April 2019 Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M70. Nose. Dusky coloured patch right nasal wall extending to cheek ?port wine stain; rosacea; ?Dx

Edited by Admin_Dermpath


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Krishnakumar subramanian

Posted

mixed inflammatory cells in superficial and mid dermis. there are some non communicating sinusoidal vessels. some of them have prominent endothelial cells especially sen in image 4, in the dermis there are extravasted RBCs and siderophages.  may be some IHC will be useful

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Krishnakumar subramanian

Posted

sir, do we need a Ki 67 stain  and ERG stain to know the proliferation status before we conclude it as angiosarcoma

 

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Dr. Richard Carr

Posted

Yes I thought there were sufficient features here for a diagnosis of angiosarcoma. ERG should show the same irrecular branching pattern as already highlighted in the endothelial markers above. I'm not sure I'd find Ki67 helpful or definitive. We would very much have to consider the clinical context in the diagnosis.

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