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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2273 - 28 February 2019 Posted By: Raul Perret

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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F80, 15 mm finger lesion


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I think there is a perineurioma component, so favor a hybrid schwannoma and perineurioma.

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Well demarcated multinodular myxoid spindle cell nodules, fingers, I am also thinking nerve sheath myxoma. S100, GFAP.

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Alex-Ventura-Leon

Posted

Nerve Sheath Myxoma is my first thought, but agree whit the above differentials.

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Raul Perret

Posted

The diagnosis was dermal nerve sheath myxoma. The multinodular appearance and the finger location is typical of this entity. Plexiform schwannoma is typically hypercellular (only Antoni A areas) and acral location is quite infrequent. 

PSX_20190214_193350.jpg

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