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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2232 - 2 January 2019 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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55 year old male with lesion on back


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Mariantonieta Tirado

Posted

Sebaceoma. There are a couple of mature sebocytes in the upper left of the last picture with scalloped nuclei The immature cells are small and so are their nucleoli. Don’t see necrosis or mitotic figures.

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Meenakshi Batrani

Posted

Sebaceoma, I can see some sebocytes. 

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Alex-Ventura-Leon

Posted

Sebaceoma for me too.

I would search for Muir Torre Syndrome.

The distinction betwenn Sebaceoma and Sebaceous Carcinoma is sometimes very subjective (in my opinion)

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vincenzo

Posted (edited)

Mm!! I think this is a Seborrheic Keratosis with sebaceous differentiation. The follicular infundibulum is actually the most favorite target as origin of SK. So sebaceous differentiation isn't unexpected. There are keratin cysts, as good markers of SK. 

Edited by vincenzo

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Poroma or poroid hidradenoma. ( poroid cells, cuticular cells and granulation tissue like stroma).

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Raul Perret

Posted

I think I was wrong initially. It looks more like poroma (particularly the architecture), it is super blue hard to interpret just based on these images

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I agree with Dermpath1 and Henry.The puzzling part of this tumor is the sebaceous differentiation , which has been described previously in Hidraadenomas.

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Dr. Richard Carr

Posted

I went through all the same considerations as above. I suppose it's a mixed follicular-ductal-sebaceous unit neoplasm. Could call is seborrhoeic keratosis-like poroma/hidradenoma with focal sebaceous differentiation. It's benign!

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