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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2246 - 22 January 2019 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M40. Lesion on right hand.


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AmerSM

Posted (edited)

epithelioid fibrous histiocytoma vs solitary reticulohistiocytoma

Edited by AmerSM

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Alex-Ventura-Leon

Posted

Agree. Reticulohistiocytoma for me too.

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Well defined nodular dermal infiltrate, with ground-glass cells and scattered small collections of foamy cells, is in keeping with Reticulohistiocytoma, as my Colleagues have remarked.

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Reticulohistiocytoma and fibrous histiocytoma were on my list of differential diagnosis, too. Looks like so far most people here favor reticulohistiocytoma. For my education can someone please comment on whether this lesion can be called xanthogranuloma? Great case to clarify some concepts!

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Dr. Richard Carr

Posted

It's clearly xanthogranulomatous as well as reticulohistiocytomatous (could by argued an encompassing term might be called for like solitary eruptive non-X histiocytoma or SEnXH for short). I liked the additional differential suggestion of epithelioid fibrous histiocytoma too. BTW I also thought about Spitz naevus and perineurioma but I guess these would be lower down.

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