Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2358 - 3 July 2019 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)

32 year old female with history of severe aphthous stomatitis, who presents with rash on arms

Edited by Admin_Dermpath


  Report Record

User Feedback


IgorSC

Posted

Erythema multiforme and the oral ulcers may be associated with herpes virus infection.

Share this comment


Link to comment
share_externally

vincenzo

Posted

I don't see herpes-related changes but...yes, agree with a Steven-Johnson syndrome!

Share this comment


Link to comment
share_externally

Saman Fatah

Posted

There is sub-epidermal split at the edge of biopsy with significant interface changes and a rather dense dermal inflammation.

While SJS/TEN is a possibility (histologically in part of the specimen) more clinical information is required including drug exposure  and % BSA detachment.

I would consider a TEN-like lupus/bullous LE in the differential diagnosis, this is a rare florid acute presentation of lupus especially SLE and serology/DIF may shed more light on the relevance of this possibly in such a young female.

Share this comment


Link to comment
share_externally

Anil Patki

Posted

Erythema multiforme - drug induced

Share this comment


Link to comment
share_externally

IgorSC

Posted

16 hours ago, vincenzo said:

I don't see herpes-related changes but...yes, agree with a Steven-Johnson syndrome!

Sorry, maybe I didn´t expressed myself correctly. I think the oral lesions the patient has may be associated with herpes, and this rash on arms are due to erythema multiforme. But I liked the hypothesis of Stevens-Johnson as well.

Share this comment


Link to comment
share_externally

vincenzo

Posted

8 hours ago, IgorSC said:

Sorry, maybe I didn´t expressed myself correctly. I think the oral lesions the patient has may be associated with herpes, and this rash on arms are due to erythema multiforme. But I liked the hypothesis of Stevens-Johnson as well.

Sorry, Igor, it is me who misunderstood.

Share this comment


Link to comment
share_externally

Victor Delgado

Posted

Steven Johnson Syndrome.

Share this comment


Link to comment
share_externally

Dr. Hafeez Diwan

Posted

Erythema multifome. She presently doesn't have aphthous stomatitis (she had it in the past).  She currently has targetoid lesions.

Share this comment


Link to comment
share_externally



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...

×
×
  • Create New...