Case Number : Case 2276 - 5 March 2019 Posted By: Uma Sundram

Basal cell adenoma membranous type

Basal cell adenoma membranous type is a very interesting thought, although the location of forehead is probably very uncommon for this entity. The presence of eosinophilic globules and intralesional lymphocytes reminds me of spiradenoma. I wonder if S100 would tell these two entities apart - basal cell adenoma is supposed to have a peripheral layer of S100+ myepithelial cells.

I see ducts formations, myoepithelial differentation (for me) and hyaline stroma so im thinking in Cutaneous Mixed Tumor.

Cutaneous mixed tumor is my first thought. There is a mammary-myospherulosis-like pattern. 

My thought is cutaneous mixed tumor

Cutaneous mixed tumor. As you all know, there can be significant overlap among all adnexal tumors. This tumor was quite deep (second attempt at excision) so we asked the clinician to plan on complete removal. Management approach is far more important than classification. We elected against basal cell adenoma due to the site.

On 05/03/2019 at 08:06, vincenzo said:

Cutaneous mixed tumor is my first thought. There is a mammary-myospherulosis-like pattern. 

love your comment. agree completely, I even put spiradenoma in the ddx, even though no scattered lymphocytes seen

Spiradenoma with prominent basement membrane-like material