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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2276 - 5 March 2019 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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55 year old male with 0.8 cm lesion on forehead


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John Zhang

Posted

Basal cell adenoma membranous type is a very interesting thought, although the location of forehead is probably very uncommon for this entity. The presence of eosinophilic globules and intralesional lymphocytes reminds me of spiradenoma. I wonder if S100 would tell these two entities apart - basal cell adenoma is supposed to have a peripheral layer of S100+ myepithelial cells.

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Alex-Ventura-Leon

Posted

I see ducts formations, myoepithelial differentation (for me) and hyaline stroma so im thinking in Cutaneous Mixed Tumor.

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Cutaneous mixed tumor is my first thought. There is a mammary-myospherulosis-like pattern. 

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Dr. Mona Abdel-Halim

Posted

My thought is cutaneous mixed tumor

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Uma Sundram

Posted

Cutaneous mixed tumor. As you all know, there can be significant overlap among all adnexal tumors. This tumor was quite deep (second attempt at excision) so we asked the clinician to plan on complete removal. Management approach is far more important than classification. We elected against basal cell adenoma due to the site.

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On 05/03/2019 at 08:06, vincenzo said:

Cutaneous mixed tumor is my first thought. There is a mammary-myospherulosis-like pattern. 

love your comment. agree completely, I even put spiradenoma in the ddx, even though no scattered lymphocytes seen

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Dr. Richard Carr

Posted

Spiradenoma with prominent basement membrane-like material

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