In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

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Case Number : Case 2281 - 12 March 2019 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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55 year old woman with solitary lesion on forehead

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Krishnakumar subramanian

Posted

some tumor lobules shows contact with basal layer, basaxoid pattern with sebaceous differentiation, focal cracking artifact in image 4

? BCC with sebaceous differentiation-plan for complete excision

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Meenakshi Batrani

Posted

Sebaceoma  

Although, some lobules show >50% sebaceous differentiation, but focal sebaceous adenoma like differentiation may be present in sebaceoma, in such cases the distinction between sebaceoma and sebaceous adenoma is somewhat arbitrary Considering predominant basaloid proliferation in most lobules, I would prefer sebaceoma.

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vincenzo

Posted

Benign neoplasm of sebaceous gland( sebaceous adenoma/sebaceoma-spectrum)...but with cellular atypia. Margins are near the neoplasm, but this shows a well circumscribed lobular growth pattern. So my spot, for practical reasons, is sebaceoma with atypia. I don't think this is a sebaceous carcinoma.

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HENRY

Posted

Sebaceoma. Need check MSI , to rule out possibility of Muir-Torre syndrome.

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Uma Sundram

Posted

Sebaceoma. All MSI markers were retained, and no loss documented. The clinicians opted for complete removal.

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