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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2320 - 8 May 2019 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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59 year old female with elbow lesion (courtesy of Dr Amanda Moyer)


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IgorSC

Posted

I see some amorphous eosinohilic material around dermal vessels along with intersticial red cell extravasation and plasma cell infiltration. I think this is Nodular amyloidosis. I would recommend systemic workup in case of confirmation of the amyloid deposition after use of special stain (congo red) and polarized light.

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Krishnakumar subramanian

Posted

In the dermis there is vascular damage with deposition of fibrinous material and perivascular chronic inflammatory cells

could it be a rheumatoid nodule

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Meenakshi Batrani

Posted

Nodular amyloidosis. Workup to exclude systemic amyloidosis. 

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John Zhang

Posted

Agree amyloidosis, waiting for congo red...

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vincenzo

Posted (edited)

Sincerely I was thinking of an acquired elastotic hemangioma(cavernous type), but the  Colleagues comments are intriguing me...And the plasma cells are in keeping with amyloidosis.

Edited by vincenzo

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Dr. Hafeez Diwan

Posted

Nodular amyloidosis.

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