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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2324 - 14 May 2019 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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51 year old female with lesion on left knee. Image 4=MITF; Image 5=p16; Image 6=Ki67
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Go to records May 2019

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vincenzo

vincenzo 4

Posted

Atypical Spitzoid Tumor, probably benign. Asymmetric, with focally sovrapapillary involvement and mildly expansive ( fig1 ), but without pagetoid spread or mitotic activity or other malignant features.

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John Zhang

John Zhang 0

Posted

Agree with Vincenzo that this lesion is probably benign: Spitzoid lesion with quite a few Kamino bodies, uniform atypia, no pagetoid spread, mosaic pattern of positive p16 stain. My spot is Spitz nevus, if fig1 contains nearly the entirely lesion.

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Victor Delgado

Victor Delgado 6

Posted

Low grade dysplastic nevus

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Uma Sundram

Uma Sundram 169

Posted

Spitz nevus. Ki67 is confined to epidermal melanocytes. However, given the age of the patient, we recommended a re excision. Hope everyone is at the LDS and having a good time. Lots of great talks!

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