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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2436 - 4 November 2019 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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56F, large pigmented plaque lumbar region

Edited by Admin_Dermpath

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1 hour ago, dermpath1 said:

?Darier disease / Grover disease.

I'd like GD but..."large pigmented plaque"?

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Krishnakumar subramanian


that acantholysis could be an artefact

I am concerned with pigmented Bowens in covered area. some parakeratosis is seen. I need higher magnification

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Dear all 


Wide range of comments. The final diagnosis is HaileyHailey disease, or familial benign chronic pemphigus - note the dilapidated brick wall sign see in the second and third images :) !



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