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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2395 - 4 September 2019 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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27 year-old female with lateral to left axilla biopsy. Clinical impression: eczema


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Parakeratosis, acanthosis, dermal perivascular and periappendageal lymphocytic infiltrate and dermal mucin deposits are the salient features. I think that it's subacute cutaneous LE. Is there follicular mucinosis in the last figure? 

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Alex-Ventura-Leon

Posted

I think that follicular mucinosis (in this case) is secondary to eczema

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Follicular Mucinosis is the basic pathology. Probably inflammatory, because I don't see any atypical lymphoid cells.

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Follicular mucinosos is only a pathologic finding here, I don´t think it has any specific association in this case. This is a spongiotic dermatitis that needs to be correlated with clinical diagnosis.

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Dr. Hafeez Diwan

Posted

Indeed, there is follicular mucinosis.  The lymphocytes were CD3 and CD4 positive.  CD8 and CD7 were largely negative.  The features are therefore consistent with mycosis fungoides.

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Dr. Richard Carr

Posted

Agree some eczematous features with follicular mucinosis. I would not rush to diagnose MF without clinicopathological correlation and probably quite a bit of follow-up but obviously this may progress in time.

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