Case Number : Case 2541 - 02 April 2020 Posted By: Saleem Taibjee

Myxoid tumor with vessels and bland stellate spindle cells containing entrapped epithelial component. I would consider Superficial angiomyxoma.

1 hour ago, Meenakshi Batrani said:

Myxoid tumor with vessels and bland stellate spindle cells containing entrapped epithelial component. I would consider Superficial angiomyxoma.

Also have a similar opinion.Spindle cell lipoma is in the differentials.

Yes, superficial angiomyxoma

My thought is also superficial angiomyxoma.

Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

Superficial angiomyxoma agreed

13 hours ago, vincenzo said:

Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

Take care dear Vincenzo and stay safe!

Thanks, Anil!!!

23 hours ago, vincenzo said:

Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

God protect u all there, my heart with u all..

Thank you so much, Mona. 

Yes. This is superficial angiomyxoma. I also shared the case with Raul Perret for his expert opinion, and he also agreed.

The CD34 is shown below. In that regard, it is interesting to read the discussion above about similarity to superficial acral fibromyxoma in this case because SAF is also typically CD34 positive. S100 was negative, ruling out nerve sheath myxoma.

The entrapped epithelial elements are a good clue to the diagnosis. In this case I was struck by the sparing of the overlying dermis, instead more subcutaneous location, which seems to go against the usual textbook descriptions.

Agree