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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2541 - 02 April 2020 Posted By: Saleem Taibjee

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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65M, suspected epidermoid cyst right posterior thigh.


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Meenakshi Batrani

Posted

Myxoid tumor with vessels and bland stellate spindle cells containing entrapped epithelial component. I would consider Superficial angiomyxoma.

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dermpath1

Posted

1 hour ago, Meenakshi Batrani said:

Myxoid tumor with vessels and bland stellate spindle cells containing entrapped epithelial component. I would consider Superficial angiomyxoma.

Also have a similar opinion.Spindle cell lipoma is in the differentials.

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Dr. Mona Abdel-Halim

Posted

Yes, superficial angiomyxoma

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Eman El-Nabarawy

Posted

My thought is also superficial angiomyxoma.

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Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

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Krishnakumar subramanian

Posted

Superficial angiomyxoma agreed

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Anil Patki

Posted

13 hours ago, vincenzo said:

Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

Take care dear Vincenzo and stay safe!

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Dr. Mona Abdel-Halim

Posted

23 hours ago, vincenzo said:

Yes! This tumor looks like a superficial acral fibromyxoma, but a I saw similar examples of Superficial Angiomyxoma, resembling SAF; agree with Colleagues.

A warm hello from the "red zone"...

God protect u all there, my heart with u all..

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Saleem Taibjee

Posted

Yes. This is superficial angiomyxoma. I also shared the case with Raul Perret for his expert opinion, and he also agreed.

The CD34 is shown below. In that regard, it is interesting to read the discussion above about similarity to superficial acral fibromyxoma in this case because SAF is also typically CD34 positive. S100 was negative, ruling out nerve sheath myxoma.

The entrapped epithelial elements are a good clue to the diagnosis. In this case I was struck by the sparing of the overlying dermis, instead more subcutaneous location, which seems to go against the usual textbook descriptions.

15757_20-3-2020_13-24-44_5.0xb CD34 labelled.jpg

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