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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2555 - 22 April 2020 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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41 year-old male with biopsy from left lower back. He was recently diagnosed with CLL.
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Go to records April 2020

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Hamad

Spongiotic dermatitis with last week sign.

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Meenakshi Batrani

Meenakshi Batrani 0

Posted

Elongated mounds of parakeratosis with mild perivascular lymphocytic infiltrate. ?Could be erythema annulare centrifugum which can occur in the setting of CLL.  No eosinophils to consider eosinophilic dermatosis of hematological malignancy. 

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

On 22/04/2020 at 17:01, vincenzo said:

PAS?

Yes, any stains done?

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Dr. Hafeez Diwan

Dr. Hafeez Diwan 125

Posted

PAS was negative.  I called it resolving spongiotic dermatitis. It has the "last week" sign.

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Krishnakumar subramanian

Krishnakumar subramanian 0

Posted

• Finally, you relax in the weekend and think about what you have achieved last week, you remember (The Last Week Sign) when you see parakeratosis overlying basket weave orthokeratin indicating a no longer active dermatosis, a dermatosis that is playing itself out.Thanks Dr

 

 

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vincenzo

Very interesting, thanks to Dr Hafeez and Dr Mona!

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