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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2634 - 11 August 2020 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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35 year old female with papulonodule on left knee.


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Eman El-Nabarawy

Posted

Epithelioid fibrous histiocytoma.

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I was thinking of a Touton cell-poor xanthograsnuloma, but it should have been spared adnexa...So DF fits better, or also a solitary reticulohistiocytoma. 

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Krishnakumar subramanian

Posted

histiocytic infiltrate -

some IHC needed 

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Uma Sundram

Posted

Xanthogranuloma. A lot of overlap between reticulohistiocytoma and XG. I did not use CD163, but this marker can be used to exclude epithelioid fibrous histiocytoma. The fibrocytes in ECH will not stain w this marker.

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