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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2638 - 17 August 2020 Posted By: Iskander H. Chaudhry

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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65F, Punch biopsy left cheek. ?BCC


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Meenakshi Batrani

Posted (edited)

Desmoplastic trichoepithelioma

Edited by Meenakshi Batrani

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Krishnakumar subramanian

Posted

considering the age of the patient can we have IHC

 DT is CK20+, AR+ while MAC is usually negative for these markers.

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Dr. Mona Abdel-Halim

Posted

On 18/08/2020 at 10:12, Krishnakumar subramanian said:

considering the age of the patient can we have IHC

 DT is CK20+, AR+ while MAC is usually negative for these markers.

Agree

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Admin_Dermpath

Posted

Dr. Chaudhry final comment on the case - please see below;

 

Dear All - Thank you for your comments. 

Our differential diagnoses were MAC versus DT versus infiltrative BCC. The tumour was BerEp4 positive and CK 20. We did. It do not perform androgen receptor markers. 

The final differential was DT versus BCC. The clinician felt it was the latter and he was to perform MOHs.

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Dr. Richard Carr

Posted

Looks typical of DTE. Demonstrating reactive MC with CK20 is useful (not seen in INF BCC).

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