Case Number : Case 2731 - 24 December 2020 Posted By: Iskander H. Chaudhry

epithelioid hemangioma

However considering the age i am concerned with angiosarcoma

On 26/12/2020 at 06:17, Krishnakumar subramanian said:

epithelioid hemangioma

However considering the age i am concerned with angiosarcoma

Agree, and would like to see a pan keratin stain/Erg to rule out SCC or a METASTATIC LUNG ADENOCARCINOMA( adenosquamous). 

Dear All 

Thanks for your comments! Seasons greetings. As you say this is a tumour showing mild acanthosis and dermal islands of eosinophil epithelioid cells with clear cell change and myxoid stroma. The tumour cells show prominent nucleoli and mitotic activity. The tumour is positive for MNF116 and CK7 with membranous staining. It is negative for CD31, CEA, SMA, Desmin and S100. No lympho-vascular or perineural invasion is seen. There is no tumour necrosis. No epidermal changes are evident.

I classified this as a primary cutaneous carcinoma (likely adnexal) versus metastatic carcinoma.

thanks a lot Dr. 

Nice but Tricky case. Given the growth pattern, I do entertain the possibility of cutaneous adnexal carcinoma such as squamoid eccrine ductal carcinoma