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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2507 - 14 February 2020 Posted By: Dr. Richard Carr

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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M58. See clinical Images


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I know the type A/B/C/D of Lymphomatoid Papulosis, but type E LP is a foreign chapter for me...?Lymphomatoid Papulosis type E.

 

 

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Eman El-Nabarawy

Posted

2015 looks ALTCL.

2018 looks Lyp.

So I think of "Borderline CD30 positive lymphoproliferative disorder or CD30 positive lymphomatoid papulosis- Anaplastic large T cell lymphoma, Angioinvasive type.

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Krishnakumar subramanian

Posted

could be type E LP which has anglocentric atypical lymphoid infiltrate but need other markers for cytotoxic phenotype like granzyme/perforin and also EBV RNA in situ on the sample. Pet Scan to make sure there are no internal lesions and these cases need follow up for years

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Dr. Mona Abdel-Halim

Posted

Angioinvasive/angiodestructive LyP (type E)

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Dr. Richard Carr

Posted

Yes this was CD30+ lymphoproliferative disorder and LyP based on clinical follow-up. Agree quite and angiocentric / angiodestructive pattern. 

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