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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 2509 - 18 February 2020 Posted By: Uma Sundram

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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A 45-year-old female with a slowly growing lesion on the left upper arm.
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Go to records February 2020

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

The nuclei are blunt ended and the second image shows perinuclear vacuoles, I favor leiomyoma

 

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vincenzo

Mildly atypical...what about a low grade leiomyosarcoma?

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Krishnakumar subramanian

Krishnakumar subramanian 0

Posted

can we also consider Atypical intradermal smooth muscle neoplasm

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Uma Sundram

Uma Sundram 169

Posted

I think these things are quite difficult. This particular tumor had enough atypia and mitotic activity that we felt comfortable with leiomyosarcoma. However, distinction among atypical lesions, so called symplastic lesions and true sarcoma is not easy and is in the eye of the beholder. The advantage of a slight overcall in this case is an appropriate, conservative excision.

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